Key details
| Part number | RXSOL-60-6604-737 |
|---|---|
| Standard packing | 0.00 Box |
| Supply locations | [IODOFORM LR] manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman. Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada. [IODOFORM LR] is available in small packing as well as in bulk. Buy premium quality [IODOFORM LR] and other lab chemicals from one of the most trusted brands |
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<span style="font-size:14px;"><strong><span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">Iodoform</span> gauze is used in clinical practice for treatment of infected wounds. However, effectiveness and action mechanism of <span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">iodoform</span> gauze for removal of necrotic tissue are unknown. We therefore employed case control and biochemical studies in order to clarify the pharmacological activity of <span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">iodoform</span> gauze. A clinical study demonstrated that treatment with <span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">iodoform</span> gauze removed necrotic tissue more effectively than treatment with conventional ointments. More than 60% of <span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">iodoform</span> gauze-treated wounds were completely debrided within 2 weeks. Consistent with the clinical observation, biochemical analyses revealed clear differences in wound fluid proteins after treatment with <span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">iodoform</span> gauze or conventional gauze. The amount of macroaggregates of type I collagen from wounds were remarkably decreased in <span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">iodoform</span> gauze. Moreover, <span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">iodoform</span> gauze and <span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">iodoform</span> itself released non-aggregative type I collagen from necrotic debris in vitro. Taken together, we conclude that <span class="hlt" style="box-sizing: border-box; color: rgb(153, 0, 0);">iodoform</span> gauze efficiently removes necrotic tissue by its lytic activity for collagen fibers</strong></span></p>
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<strong><span style="color: rgb(77, 81, 86); font-family: arial, sans-serif; font-size: 14px;">The exposed sub-lethal </span><span style="font-weight: bold; color: rgb(95, 99, 104); font-family: arial, sans-serif; font-size: 14px;">doses</span><span style="color: rgb(77, 81, 86); font-family: arial, sans-serif; font-size: 14px;"> determined after LD50 range from 2.1 to 2.9 and 77.5 to 87.5 mg/L for </span><span style="font-weight: bold; color: rgb(95, 99, 104); font-family: arial, sans-serif; font-size: 14px;">iodoform</span><span style="color: rgb(77, 81, 86); font-family: arial, sans-serif; font-size: 14px;"> and chloroform,</span></strong></p>
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<span style="font-size:14px;"><strong><span style="color: rgb(0, 0, 0); font-family: "Times New Roman", stixgeneral, serif;">Zinc oxide eugenol (ZOE) has traditionally been used as a root filling material in primary teeth pulpectomy. Calcium hydroxide and iodoform (Ca(OH)</span><span style="line-height: 1.6363em; position: relative; vertical-align: baseline; bottom: -0.25em; top: 0.25em; color: rgb(0, 0, 0); font-family: "Times New Roman", stixgeneral, serif;">2</span><span style="color: rgb(0, 0, 0); font-family: "Times New Roman", stixgeneral, serif;">/iodoform) may have advantages as a root canal filling material to evaluate treatment success of Ca(OH)</span><span style="line-height: 1.6363em; position: relative; vertical-align: baseline; bottom: -0.25em; top: 0.25em; color: rgb(0, 0, 0); font-family: "Times New Roman", stixgeneral, serif;">2</span><span style="color: rgb(0, 0, 0); font-family: "Times New Roman", stixgeneral, serif;">/iodoform pulpectomy in primary teeth compared with ZOE based on clinical and radiographical criteria. All human clinical studies reporting clinical and radiographical outcomes of Ca(OH)</span><span style="line-height: 1.6363em; position: relative; vertical-align: baseline; bottom: -0.25em; top: 0.25em; color: rgb(0, 0, 0); font-family: "Times New Roman", stixgeneral, serif;">2/</span><span style="color: rgb(0, 0, 0); font-family: "Times New Roman", stixgeneral, serif;">iodoform compared with ZOE in primary teeth pulpectomy were identified in digital bibliographic databases.</span></strong></span></p>
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